Immunofluorescence staining of 14 DIV cultured rat cortical neuron with N355/1. Image courtesy of Brad Elmer and Kim McAllister (UCD).

Immunofluorescence staining of 14 DIV cultured rat cortical neuron with N355/1. Image courtesy of Brad Elmer and Kim McAllister (UCD).

Adult rat hippocampus immunohistochemistry.

Adult rat hippocampus immunohistochemistry.

Adult rat brain membrane immunoblot.

Adult rat brain membrane immunoblot.

Transfected cell immunoblot: extracts of COS cells transiently transfected with untagged GluR1, GluR2 or Kv2.1 plasmid and probed with N355/1 (left), L21/32 (middle) or N52A/42 (right) TC supe.

Transfected cell immunoblot: extracts of COS cells transiently transfected with untagged GluR1, GluR2 or Kv2.1 plasmid and probed with N355/1 (left), L21/32 (middle) or N52A/42 (right) TC supe.

from NeuroMab

GluA1/GluR1 glutamate receptor (7x-327)

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Volume: Purified: 100 µL; Purified Trial: 20 µL; TC Supernatant: 5 mL

Concentration: Purified: 1 mg/mL; TC Supernatant: Lot Specific

Clonality: Monoclonal

Form: Purified and TC Supernatant Available (select your preferred form, size and quantity before clicking "Add to Cart")

Host Species: Mouse

Immunogen: Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (also known as Glutamate receptor 1, Ionotropic AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, GLUH1 and Gria1, accession number P19490) Mouse: 99% identity (388/389 amino acids identical) Human: 97% identity (379/389 amino acids identical) 100% identity between Flip and Flop isoforms >50% identity with GluA2/GluR2, GluA3/GluR3 and GluA4/GluR4

Target Description: Glutamate receptor 1 or GluA1/GluR1 glutamate receptor is a member of the glutamate-gated ion channel family. GluR1 funcitons as an excitatory neurotransmitter at many synapses in the central nervous system and is widely expressed in brain. Mutations in the GluR1 gene are associated with cerebral cortical dysplasia, Status Epilepticus, and depression.

Gene ID: Gria1 Glur1

Antibody Registry ID (RRID): AB_2315840

Physical State: Liquid

Validation and Application Notes

Molecular Weight: 100 kDa

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.


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