Adult rat hippocampus immunohistochemistry.

Adult rat hippocampus immunohistochemistry.

Adult rat brain membrane immunoblot.

Adult rat brain membrane immunoblot.

Immunoblot against crude membranes from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] probed with N133/21 (left) or N52A/42 (right) TC supe.

Immunoblot against crude membranes from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] probed with N133/21 (left) or N52A/42 (right) TC supe.

Immunoblot against lysates from wild-type (+/+) and RGS14 knockout (-/-) mouse brains probed with N133/21. Data courtesy of John Hepler (Emory).

Immunoblot against lysates from wild-type (+/+) and RGS14 knockout (-/-) mouse brains probed with N133/21. Data courtesy of John Hepler (Emory).

RGS14 (7x-170)

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Details

Concentration: 1 mg/mL

Clonality: Monoclonal

Form: Purified

Host Species: Mouse

Immunogen: Fusion protein amino acids 1-544 (full-length) of rat RGS14 (also known as Regulator of G-protein signaling 14, RAP1/RAP2-interacting protein and RPIP1, accession number O08773)
Mouse: 95% identity (524/547 amino acids identical)
Human: 86% identity (475/547 amino acids identical)
45% identity with RGS12 and other RGS proteins
Epitope mapped to within amino acids 444-490 (between 2nd Ras-binding
GoLoco domains, PDAKTREASSIPPCRSQGCLPRTQTKDSHLPPLSSSLSVEDASGSTG, 2014 Evans et al J Comp Neurol)
Mouse: 85% identity (40/47 amino acids identical)
Human: 51% identity (24/47 amino acids identical)

Gene ID: Rgs14

Antibody Registry ID (RRID): AB_2179931

Physical State: Liquid

Validation and Application Notes

Molecular Weight: 60 kDa

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.


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Citations


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