Adult WT and KO mouse hippocampus immunofluorescence with N206A/8 (green) and KC rabbit anti- Kv2.1 (red). Brain samples courtesy of Albee Messing, University of Wisconsin at Madison.

Adult WT and KO mouse hippocampus immunofluorescence with N206A/8 (green) and KC rabbit anti- Kv2.1 (red). Brain samples courtesy of Albee Messing, University of Wisconsin at Madison.

Adult WT and KO mouse hippocampus immunofluorescence with N206A/8 (green) and KC rabbit anti- Kv2.1 (red). Brain samples courtesy of Albee Messing, University of Wisconsin at Madison.

Adult WT and KO mouse hippocampus immunofluorescence with N206A/8 (green) and KC rabbit anti- Kv2.1 (red). Brain samples courtesy of Albee Messing, University of Wisconsin at Madison.

Immunoblot versus low speed pellet samples from rat brain (RBLSP) and wild-type (WT), GFAP knockout (KO) and GFAP-R416W mutant knockin (KI) mice and probed with N206A/8 (left), mutant control(middle) and N52A/42 (right). Mutant control courtesy of Michael Brenner, University of Alabama at Birmingham.

Immunoblot versus low speed pellet samples from rat brain (RBLSP) and wild-type (WT), GFAP knockout (KO) and GFAP-R416W mutant knockin (KI) mice and probed with N206A/8 (left), mutant control(middle) and N52A/42 (right). Mutant control courtesy of Michael Brenner, University of Alabama at Birmingham.

Adult WT and KO mouse hippocampus immunofluorescence with N206A/8 (green) and KC rabbit anti- Kv2.1 (red). Brain samples courtesy of Albee Messing, University of Wisconsin at Madison.
Adult WT and KO mouse hippocampus immunofluorescence with N206A/8 (green) and KC rabbit anti- Kv2.1 (red). Brain samples courtesy of Albee Messing, University of Wisconsin at Madison.
Immunoblot versus low speed pellet samples from rat brain (RBLSP) and wild-type (WT), GFAP knockout (KO) and GFAP-R416W mutant knockin (KI) mice and probed with N206A/8 (left), mutant control(middle) and N52A/42 (right). Mutant control courtesy of Michael Brenner, University of Alabama at Birmingham.

from NeuroMab

GFAP (7x-240)

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Volume: Purified: 100 µL; Purified Trial: 20 µL; TC Supernatant: 5 mL

Concentration: Purified: 1 mg/mL; TC Supernatant: Lot Specific

Clonality: Monoclonal

Form: Purified and TC Supernatant Available (select your preferred form, size and quantity before clicking "Add to Cart")

Host Species: Mouse

Immunogen: Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (also known as Glial fibrillary acidic protein, accession number P14136)
Rat: 100% identity (12/12 amino acids identical)
Mouse: 100% identity (12/12 amino acids identical) >50% identity with other proteins (Vimentin, Desmin, Tumor protein p73 and Peripherin)

Target Description: Glial fibrillary acidic protein (GFAP) is an intermediate filament with many different isoforms, and acts as a structural protein in the cytoskeleton. It is expressed in astrocytes in brain and is often used as an astrocyte marker. GFAP is belived to be involved in many CNS processes including cell communication and mitosis. GFAP has been found to be involved in Alexander disease and Wernicke's encephalopathy.

Gene ID: GFAP

Antibody Registry ID (RRID): AB_10672299

Physical State: Liquid

Validation and Application Notes

Molecular Weight: 50 kDa

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.


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