Western blot of human striatal lysate showing specific immunolabeling of the ~88 kDa DAT protein.

Western blot of human striatal lysate showing specific immunolabeling of the ~88 kDa DAT protein.

Anti-Dopamine Transporter, C-Terminus, Human (431-DATC)

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Product Details


Details

The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996).

Volume: 100 µL

Concentration: Lot Specific

Clonality: Polyclonal

Form: Antigen Affinity Purified from Pooled Serum

Host Species: Rabbit

Species Reactivity: Human, Mouse, non-Human primate

Applications: WB, IHC

Immunogen: Synthetic peptide corresponding to amino acid residues from the intracellular C-terminal region conjugated to KLH

Protein Name / Synonyms: DAT

Gene ID: SLC6A3

Antibody Registry ID (RRID): AB_2492076

Physical State: Liquid

Conjugate: Unconjugated

Buffer: 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Validation and Application Notes

Molecular Weight: 80

Storage

-20 C

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.


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