Western blot of rat testes lysate showing specific immunolabeling of the ~58 kDa FTO protein.
Anti-FTO (Fat Mass And Obesity Related Protein) Antibody
FTO (Fat mass and obesity related protein)
The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that FTO is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009).
Protein G purified culture supernatant
Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH(Human)
Human, Mouse, Rat
100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.