Anti-GluA1/GluR1 Glutamate Receptor Antibody (N355/1)

Primary Antibody
Mouse, Rat
Gria1 Glur1
100 kDa

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Anti-GluA1/GluR1 Glutamate Receptor Antibody
SKU: 75-327

Volume: 100 µL
Sale price$361

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Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
34289359not listedLi, L., et al. 2021. α2δ-1 switches the phenotype of synaptic AMPA receptors by physically disrupting heteromeric subunit assembly. Cell Reports, 109396.
32604880not listedGarcía, F., et al. 2020. Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation. Marine Drugs, 335.
Immunocytochemistry: Mouse
PMID Dilution Publication
279869281:500Lee, S.J., et al. 2017. Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses. Journal of Neuroscience, 1062-1080.
Immunocytochemistry: Rat
PMID Dilution Publication
372701561:100Nuwer, JL, et al. 2023. Long-term a5 GABA A Receptor Negative Allosteric Modulator Treatment Reduces NMDAR-mediated Neuronal Excitation and Maintains Basal Neuronal Inhibition. Neuropharmacology, 109587.
351776161:250Hruska, M., et al. 2022. Nanoscale rules governing the organization of glutamate receptors in spine synapses are subunit specific. Nature communications, 920.
34408636not listedMartin, E.E., et al. 2021. Interaction and Subcellular Association of PRRT1/SynDIG4 With AMPA Receptors. Frontiers in Synaptic Neuroscience, 705664.
34289359not listedLi, L., et al. 2021. α2δ-1 switches the phenotype of synaptic AMPA receptors by physically disrupting heteromeric subunit assembly. Cell Reports, 109396.
25918374not listedVarea, O., et al. 2015. Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons.. PNAS USA, 6176-81.
Immunohistochemistry: Mouse
PMID Dilution Publication
336132571:10Sahasrabudhe, A., et al. 2021. Cyfip1 Regulates SynGAP1 at Hippocampal Synapses. Frontier in Synaptic Neuroscience, 581714.
330063151:300Chen, C., et al. 2020. Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations. Elife, e58997.
309528131:500Yennawar, M., et al. 2019. AMPA Receptor Dysregulation and Therapeutic Interventions in a Mouse Model of CDKL5 Deficiency Disorder. Journal of Neuroscience, 4814-4828.
25352748not listedde Andrade, G.B., et al. 2014. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina.. Mol Vis, 1422-33.
Immunohistochemistry: Rat
PMID Dilution Publication
32726631not listedHolderith, N., et al. 2020. A High-Resolution Method for Quantitative Molecular Analysis of Functionally Characterized Individual Synapses. Cell Reports, 107968.
31604597not listedSchwenk, J., et al. 2019. An ER Assembly Line of AMPA-Receptors Controls Excitatory Neurotransmission and Its Plasticity. Neuron, 680-692.
Western Blot: Human
PMID Dilution Publication
342893591:1000Li, L., et al. 2021. α2δ-1 switches the phenotype of synaptic AMPA receptors by physically disrupting heteromeric subunit assembly. Cell Reports, 109396.
Western Blot: Mouse
PMID Dilution Publication
373056961:1000Opland, C, et al. 2023. Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity. iScience, 106905.
371466101:1000Li, L, et al. 2023. Tiam1 coordinates synaptic structural and functional plasticity underpinning the pathophysiology of neuropathic pain. Neuron, 2038-2050.
370784491:5000Yokokawa, T., et al. 2023. Altered Expression of Synaptic Proteins and Adhesion Molecules in the Hippocampus and Cortex Following the Onset of Diabetes in Nonobese Diabetic Mice. Physiological Reports, e15673.
367750971:1000Gruol, D.L., et al. 2023. Neuroimmune Interactions with Binge Alcohol Drinking in the Cerebellum of IL-6 Transgenic Mice. Neuropharmacology, 109455.
366813591:5000Woodburn, S.C., et al. 2023. Depletion of Microglial BDNF Increases Susceptibility to the Behavioral and Synaptic Effects of Chronic Unpredictable Stress. Brain, Behavior, and Immunity, 127-138.
36517241not listedChambon, J., et al. 2023. Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease. The Journal of Neuroscience, 672-680.
365195421:1000Ru, Q., et al. 2022. TIAM1-Mediated Synaptic Plasticity Underlies Comorbid Depression-like and Ketamine Antidepressant-like Actions in Chronic Pain. The Journal of Clinical Investigation, e158545.
364651121:1000Mendoza, M.L., et al. 2022. KIBRA Regulates Activity-Induced AMPA Receptor Expression And Synaptic Plasticity In An Age-Dependent Manner. Iscience, 105623.
33613257not listedSahasrabudhe, A., et al. 2021. Cyfip1 Regulates SynGAP1 at Hippocampal Synapses. Frontier in Synaptic Neuroscience, 581714.
332984401:1000Cao, Q., et al. 2020. Targeting histone K4 trimethylation fortreatment of cognitive and synaptic deficits in mouse models of Alzheimer’s disease. Science Advances, eabc8096.
331584441:1000Espinoza, S., et al. 2020. Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG. BMC Biology, 164.
326345321:1000Gruol, D.L., et al. 2020. Alcohol and IL-6 Alter Expression of Synaptic Proteins in Cerebellum of Transgenic Mice With Increased Astrocyte Expression of IL-6. Neuroscience, 124-137.
32160554not listedDe Rossi, P., et al. 2020. Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation. Cell Reports, 3520-3535.
312164241:500Troyano-Rodriguez, E., et al. 2019. PRRT1 regulates basal and plasticity-induced AMPA receptor trafficking. Molecular Cell Neuroscience, 155-163.
312007421:1000Micci, M.A., et al. 2019. Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes. Molecular neurodegeneration, 25.
306253211:1000Ribic, A., et al. 2019. Synapse-Selective Control of Cortical Maturation and Plasticity by Parvalbumin-Autonomous Action of SynCAM 1. Cell reports, 381-393.
303019471:2000Park, M.J., et al. 2018. Stress-induced changes in social dominance are scaled by AMPA-type glutamate receptor phosphorylation in the medial prefrontal cortex. Scientific Reports, 15008.
29654490not listedRivera, D.S., et al. 2018. Long-Term, Fructose-Induced Metabolic Syndrome-Like Condition Is Associated with Higher Metabolism, Reduced Synaptic Plasticity and Cognitive Impairment in Octodon degus. molecular neurobiology, 9169-9187.
291732811:1000Levenga, J., et al. 2017. AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity. Elife, e30640.
288648261:500Tanabe, Y., et al. 2017. IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α. Nature communications, 408.
27334260not listedHuang, L., et al. 2016. Post-anesthesia AMPA receptor potentiation prevents anesthesia-induced learning and synaptic deficits. Science translational medicine, 344ra85.
27066908not listedVingtdeux, V., et al. 2016. CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice. Scientific Reports, 24250.
268185201:1000Bellizzi, M.J., et al. 2016. Platelet-Activating Factor Receptors Mediate Excitatory Postsynaptic Hippocampal Injury in Experimental Autoimmune Encephalomyelitis. Journal of Neuroscience, 1336-46.
260897781:1000Tempia,F., et al. 2015. Parallel fiber to Purkinje cell synaptic impairment in a mouse model of spinocerebellar ataxia type 27.. Front Cell Neurosci., 205.
25771393not listedCristino, L., et al. 2015. d-Aspartate oxidase influences glutamatergic system homeostasis in mammalian brain.. Neurobiol Aging, 1890-1902.
24360280not listedParkhurst, C.N., et al. 2013. Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.. Cell, 1596-609.
Western Blot: Rat
PMID Dilution Publication
350381781:1000Zhou, J.J., et al. 2022. α2δ-1 Protein Promotes Synaptic Expression of Ca2+ Permeable-AMPA Receptors by Inhibiting GluA1/GluA2 Heteromeric Assembly in the Hypothalamus in Hypertension. Journal of neurochemistry, .
34408636not listedMartin, E.E., et al. 2021. Interaction and Subcellular Association of PRRT1/SynDIG4 With AMPA Receptors. Frontiers in Synaptic Neuroscience, 705664.
34375626not listedMoraga-Amaro, R., et al. 2021. Prenatal fluoxetine impairs non-hippocampal but not hippocampal memory in adult male rat offspring. Neuropharmacology, 108751.
342893591:1000Li, L., et al. 2021. α2δ-1 switches the phenotype of synaptic AMPA receptors by physically disrupting heteromeric subunit assembly. Cell Reports, 109396.
34227061not listedNagaraja, R.Y., et al. 2021. W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34. Molecular Neurobiology, 4921-4943.
339949401:1000Bach, E.C., et al. 2021. Chronic Ethanol Exposures Leads to a Negative Affective State in Female Rats That Is Accompanied by a Paradoxical Decrease in Ventral Hippocampus Excitability. Frontier in Neuroscience, 669075.
322224741:1000Mazzocchetti, P. , et al. 2020. Low doses of Perampanel protect striatal and hippocampal neurons against in vitro ischemia by reversing the ischemia-induced alteration of AMPA receptor subunit composition. Neurobiology of Disease, 104848.
318010621:1000Paskus, J.D., et al. 2019. Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action. Cell reports, 2944-2952.e5.
30989630not listedMarcello, E., et al. 2019. Amyloid-β Oligomers Regulate ADAM10 Synaptic Localization Through Aberrant Plasticity Phenomena. Molecular Neurobiology, 7136-7143.
309273621:500Durante, V., et al. 2019. Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alteration. Brain, 1365-1385.
307590951:1000Neumann, J.R, et al. 2019. The primate-specific peptide Y-P30 regulates morphological maturation of neocortical dendritic spines. Plos One, e0211151.
30181277not listedZhang, J., et al. 2018. Glutamate-activated BK channel complexes formed with NMDA receptors. PNAS, E9006-E9014.
29898386not listedOpazo, P., et al. 2018. CaMKII Metaplasticity Drives Aβ Oligomer-Mediated Synaptotoxicity. Cell reports, 3137-3145.
293972831:1000Piva, A., et al. 2018. The metaplastic effects of NMDA receptors blockade on reactivation of instrumental memories in rats. Neurobiology of learning and memory, 87-96.
29218323not listedZhang, L., et al. 2017. SAP97 Binding Partner CRIPT Promotes Dendrite Growth In Vitro and In Vivo. eNeuro, 0175-17.2017.
28902836not listedPenn, A.C., et al. 2017. Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors. Nature, 384-388.
28823933not listedStanic, J., et al. 2017. Rabphilin 3A: A novel target for the treatment of levodopa-induced dyskinesias. Neurobiology of Disease, 54-64.
281521041:2000von Ossowski, L., et al. 2017. Cysteine 893 is a target of regulatory thiol modifications of GluA1 AMPA receptors. Plos One, e0171489.
275653501:1000Loh, K.H., et al. 2016. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell, 1295-1307.
272711961:1000Gross, G.G., et al. 2016. An E3-ligase-based method for ablating inhibitory synapses. Nature Methods, 673-8.
241030311:500Luo, P., et al. 2013. Downregulation of postsynaptic density-95-interacting regulator of spine morphogenesis reduces glutamate-induced excitotoxicity by differentially regulating glutamate receptors in rat cortical neurons.. FEBS J, 6114-27.
Additional Publications: Unspecified
PMID Publication
26714288Rodrigo, M.A., et al. 2016. Dopamine receptor D5 deficiency results in a selective reduction of hippocampal NMDA receptor subunit NR2B expression and impaired memory.. Neuropharmacology., 222-235.
26306919Lv, J.M., et al. 2015. The Noncompetitive AMPAR Antagonist Perampanel Abrogates Brain Endothelial Cell Permeability in Response to Ischemia: Involvement of Claudin-5. Cellular and Molecular Neurobiology, 745-53.

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