Anti-Kv2.1 K+ Channel Antibody (K89/34)


Primary Antibody
Human, Mouse, Rat
K89/34
IHC, IP, WB
Mouse
Purified
Kcnb1
105-125 kDa (varies with cell background due to phosphorylation)

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Anti-Kv2.1 K+ Channel Antibody
SKU: 75-014

Volume: 100 µL
Price:
Sale price$345


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Product Specific References for Applications and Species

Electrophysiology: Rat
PMID Dilution Publication
338541810.5 µg/mLDallas, M.L., et al. 2021. Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2. 1. Scientific Reports, 8194.
Immunocytochemistry: Hamster
PMID Dilution Publication
31682765not listedYu, W., et al. 2019. Complexes formed with integrin-α5 and KCNB1 potassium channel wild type or epilepsy-susceptibility variants modulate cellular plasticity via Ras and Akt signaling. The FASEB Journal, 14680-9.
Immunocytochemistry: Human
PMID Dilution Publication
300916551:5 (supe)Kirmiz, M., et al. 2018. Remodeling neuronal ER–PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels. Molecular Neurobiology of the Cell, 2410-32.
26503721not listedThiffault, I., et al. 2015. A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.. The Journal of General Physiology, 399-410.
Immunocytochemistry: Mouse
PMID Dilution Publication
3443561510 µg/mLNewkirk, G.S., et al. 2022. Kv2. 1 potassium channels regulate repetitive burst firing in extratelencephalic neocortical pyramidal neurons. Cerebral Cortex, 1055-76.
342804891:500Ding, T., et al. 2021. Kv2.1 expression in giant reticular neurons of the postnatal mouse brain. Journal of Chemical Neuroanatomy, 102005.
316008261:2 (supe)Kang, S.K., et al. 2019. Spectrum of KV2.1 Dysfunction in KCNB1‐Associated Neurodevelopmental Disorders. Annals of Neurology, 899-912.
280659421:100Casanovas, A., et al. 2017. Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury. Scientific Reports, 40155.
20853508not listedHermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310.
Immunocytochemistry: Rat
PMID Dilution Publication
3159486610 µg/mLKirmiz, M., et al. 2019. Neuronal ER–plasma membrane junctions organized by Kv2–VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis. Journal of Biological Chemistry, 17735-57.
306673601:10 (supe)Andrews, N.P., et al. 2019. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain. eLife, e43322.
29395909not listedBerger, S.L., et al. 2018. Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment. Neuron, 555-570.
26442584not listedCobb, M.M., et al. 2015. Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells.. The Journal of Biological Chemistry, 29189-201.
20853508not listedHermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310.
Immunohistochemistry: Hamster
PMID Dilution Publication
31591393not listedYu, W., et al. 2017. Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain. Cell Death & Disease, e2737.
28383553not listedYu, W., et al. 2017. Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain. Cell Death & Disease, e2737.
Immunohistochemistry: Human
PMID Dilution Publication
294832851:800Gayet-Primo, J., et al. 2018. Heteromeric KV2/KV8. 2 channels mediate delayed rectifier potassium currents in primate photoreceptors. Journal of Neuroscience, 3414-27.
Immunohistochemistry: Mouse
PMID Dilution Publication
36130488not listedCserép, C., et al. 2022. Microglial Control of Neuronal Development via Somatic Purinergic Junctions. Cell Reports, 111369.
352012681:500Császár, E., et al. 2022. Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions. The Journal of experimental medicine, .
346524201:1500Inamdar, S.M., et al. 2022. Differential impact of Kv8. 2 loss on rod and cone signaling and degeneration. Human Molecular Genetics, 1035-50.
34825141not listedBuettner, J.M., et al. 2021. Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models. iScience, 103376.
33333928not listedSong, M.Y., et al. 2020. Tyrosine Phosphorylation of the Kv2. 1 Channel Contributes to Injury in Brain Ischemia. International Journal of Molecular Sciences, 9538.
329374501:200Schulien, A.J., et al. 2020. Targeted disruption of Kv2.1-VAPA association provides neuroprotection against ischeemic stroke in mice by declustering Kv2.1 channels. Science Advances, eaaz8110.
326846341:1000Asede, D., et al. 2020. Deletion of NRXN1α impairs long-range and local connectivity in amygdala fear circuit. Translational Pyschiatry, 242.
319870081:500Varga, D.P., et al. 2020. Microglia alter the threshold of spreading depolarization and related potassium uptake in the mouse brain. Journal of Cerebral Blood Flow and Metabolism, S67-80.
31831638not listedCserép, C., et al. 2020. Microglia monitor and protect neuronal function through specialized somatic purinergic junctions. Science, 528-537.
316641631:1000Thiebaud, N., et al. 2019. A unique olfactory bulb microcircuit driven by neurons expressing the precursor to glucagon-like peptide 1. Scientific Reports, 15542.
313452701:100Nishino, K., et al. 2019. Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1−Akt signaling pathway. Acta Neuropathologica Communications, 118.
309129771:100Salvany, S., et al. 2019. Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair. The FASEB Journal, 7833-51.
30050035not listedWei, Y., et al. 2018. Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer’s disease. Cell Death & Disease, 820.
300126961:10 (supe)Kirmiz, M., et al. 2018. Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum–Plasma Membrane Junctions in Mammalian Brain Neurons. The Journal of Neuroscience, 7562-84.
299548471:1000Rhomberg, T., et al. 2018. Vasoactive Intestinal Polypeptide-Immunoreactive Interneurons within Circuits of the Mouse Basolateral Amygdala. The Journal of Neuroscience, 6983-7003.
295023441:1000Dukkipati, S.S., et al. 2018. The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis. The Journal of Physiology, 1723-45.
29403353not listedBishop, H.I., et al. 2018. Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons.. Frontiers in Molecular Neuroscience, 1.
288562405 µg/mLPalacio, S., et al. 2017. Heterogeneity in Kv2 Channel Expression Shapes Action Potential Characteristics and Firing Patterns in CA1 versus CA2 Hippocampal Pyramidal Neurons. eNeuro, ENEURO.0267-17.2017.
280607011:1000Veres, J.M., et al. 2017. Perisomatic GABAergic synapses of basket cells effectively control principal neuron activity in amygdala networks. eLife, e20721.
277981881:100Yu, W., et al. 2016. Oxidation of KCNB1 Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury.. Journal of Neuroscience, 11084-11096.
268918471:250Lasiene, J., et al. 2016. Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.. Acta Neuropathologica Communications, 15.
249629011:100Mandikian, D., et al. 2014. Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors.. Journal of Comparative Neurology, 3555-74.
24494598not listedSpeca, D.J., et al. 2014. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.. Genes, Brain and Behavior, 394-408.
20853508not listedHermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310.
Immunohistochemistry: Non-Human Primate
PMID Dilution Publication
347166171:300Muñoz, Y., et al. 2021. Light microscopic and heterogeneity analysis of astrocytes in the common marmoset brain.. Journal of Neuroscience Research, 3121-3147.
Immunohistochemistry: Rat
PMID Dilution Publication
33333928not listedSong, M.Y., et al. 2020. Tyrosine Phosphorylation of the Kv2. 1 Channel Contributes to Injury in Brain Ischemia. International Journal of Molecular Sciences, 9538.
32726631not listedHolderith, N., et al. 2020. A High-Resolution Method for Quantitative Molecular Analysis of Functionally Characterized Individual Synapses. Cell Reports, 107968.
3159486610 µg/mLKirmiz, M., et al. 2019. Neuronal ER–plasma membrane junctions organized by Kv2–VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis. Journal of Biological Chemistry, 17735-57.
247232631:250Dufour, M.A., et al. 2014. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development.. Journal of Neuroscience Research, 981-99.
22675541not listedManning, C.F., et al. 2012. Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importance.. PLoS One, e38313.
20853508not listedHermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310.
Immunoprecipitation: Mouse
PMID Dilution Publication
3092257010 µgYu, W., et al. 2019. Oxidation of KCNB1 potassium channels in the murine brain during aging is associated with cognitive impairment. Biochemical and Biophysical Research Communications, 665-9.
SDS-digested freeze fracture replica-labeling: Mouse
PMID Dilution Publication
291273661:100Szoboszlay, M., et al. 2017. Objective quantification of nanoscale protein distributions. Scientific Reports, 15240.
SDS-digested freeze fracture replica-labeling: Rat
PMID Dilution Publication
291273661:100Szoboszlay, M., et al. 2017. Objective quantification of nanoscale protein distributions. Scientific Reports, 15240.
Western Blot: Hamster
PMID Dilution Publication
292643901:250Calhoun, J.D., et al. 2017. Characterization of a KCNB1 variant associated with autism, intellectual disability, and epilepsy. Neurology Genetics, e198.
Western Blot: Human
PMID Dilution Publication
341374431:1000Maverick, E.E., et al. 2021. Kv2 channel–AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking. Journal of Cell Science, jcs256339.
32284408not listedMöller, L., et al. 2020. Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations. PNAS, 9365-76.
294832851:800Gayet-Primo, J., et al. 2018. Heteromeric KV2/KV8. 2 channels mediate delayed rectifier potassium currents in primate photoreceptors. Journal of Neuroscience, 3414-27.
289386411:1000Liu, X., et al. 2017. Potential independent action of sigma receptor ligands through inhibition of the Kv2.1 channel. Oncotarget, 59345-58.
28432142not listedVullhorst, D., et al. 2017. Structural similarities between neuregulin 1–3 isoforms determine their subcellular distribution and signaling mode in central neurons. Journal of Neuroscience, 5232-5249.
28119464not listedNystoriak, M.A., et al. 2017. Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes. Science Signaling, eaaf9647.
26503721not listedThiffault, I., et al. 2015. A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.. The Journal of General Physiology, 399-410.
251644381:500Torkamani, A., et al. 2014. De novo KCNB1 mutations in epileptic encephalopathy.. Annals of Neurology, 529-40.
Western Blot: Mouse
PMID Dilution Publication
331322032 ug/mLHawkins,N.A., et al. 2021. Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant. Neurobiology of Disease, 105141.
333930911:200Zhou, L., et al. 2020. Transient receptor potential vanilloid 4 activation inhibits the delayed rectifier potassium channels in hippocampal pyramidal neurons: An implication in pathological changes following pilocarpine-induced status epilepticus. Journal of Neuroscience Research, 914-26.
33333928not listedSong, M.Y., et al. 2020. Tyrosine Phosphorylation of the Kv2. 1 Channel Contributes to Injury in Brain Ischemia. International Journal of Molecular Sciences, 9538.
29265365not listedChao, R.Y., et al. 2018. Defective trafficking of Kv2.1 channels in MPTP-induced nigrostriatal degeneration. Journal of Neurochemistry, 483-97.
285046711:5 (supe)Fletcher, E.V., et al. 2017. Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy. Nature Neuroscience, 905-16.
26538660not listedBishop, H.I., et al. 2015. Distinct Cell- and Layer-Specific Expression Patterns and Independent Regulation of Kv2 Channel Subtypes in Cortical Pyramidal Neurons.. Journal of Neuroscience, 14922-42.
26027736not listedVullhorst, D., et al. 2015. A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling.. Nature Communications, 7222.
256708601:2 (supe)Nieves-Cintrón, M., et al. 2015. Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes.. The Journal of Biological Chemistry, 7918-29.
24494598not listedSpeca, D.J., et al. 2014. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.. Genes, Brain and Behavior, 394-408.
20853508not listedHermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310.
Western Blot: Rat
PMID Dilution Publication
33333928not listedSong, M.Y., et al. 2020. Tyrosine Phosphorylation of the Kv2. 1 Channel Contributes to Injury in Brain Ischemia. International Journal of Molecular Sciences, 9538. 3159486610 µg/mLKirmiz, M., et al. 2019. Neuronal ER–plasma membrane junctions organized by Kv2–VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis. Journal of Biological Chemistry, 17735-57. 312406011:1000Vullhorst, D., et al. 2019. NMDA receptors regulate neuregulin 2 binding to ER-PM junctions and ectodomain release. . Molecular neurobiology, 8345-8363. 28768770not listedWu, Y., et al. 2017. NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic β-cells. Journal of Biological Chemistry, 15512-24. 28432142not listedVullhorst, D., et al. 2017. Structural similarities between neuregulin 1–3 isoforms determine their subcellular distribution and signaling mode in central neurons. Journal of Neuroscience, 5232-5249. 22675541not listedManning, C.F., et al. 2012. Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importance.. PLoS One, e38313. 20853508not listedHermanstyne, T.O., et al. 2010. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice.. Journal of Comparative Neurology, 4298-310.
Additional Publications: Unspecified
PMID Publication
35238051Colecraft, H.M., et al. 2022. Controlling ion channel function with renewable recombinant antibodies. The Journal of Physiology, 2023-36.
26890139Frazzini, V., et al. 2016. Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer''s disease mouse model.. Cell Death & Disease, e2100.
26240432Peltola, M.A., et al. 2016. AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes.. Schizophrenia Bulletin, 191-201.
26453299Wu, Y., et al. 2015. Concerted Trafficking Regulation of Kv2.1 and KATP Channels by Leptin in Pancreatic β-Cells.. The Journal of Biological Chemistry, 29676-90.
26442584Cobb, M.M., et al. 2015. Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells.. The Journal of Biological Chemistry, 29189-201.
26205295El Gebeily, G., et al. 2015. Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart.. Journal of Molecular and Cellular Cardiology, 85-94.
26115091He, K., et al. 2015. Regulation of Pro-Apoptotic Phosphorylation of Kv2.1 K+ Channels.. PLoS One, e0129498.
25908859Fox, P.D., et al. 2015. Induction of stable ER-plasma-membrane junctions by Kv2.1 potassium channels.. Journal of Cell Science, 2096-105.
25568127Liu, J., et al. 2015. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation.. Journal of Neuroscience, 352-65.
25525262Ednie, A.R., et al. 2015. Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly.. The Journal of Biological Chemistry, 2769-83.
25182224Jensen, C.S., et al. 2015. Live-cell imaging of post-golgi transport vesicles in cultured hippocampal neurons.. Cell Molecular Neurobiology, 123-35.
25674050Moutal, A., et al. 2014. Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides.. Frontiers in Neuroscience, 471.
25260053Krasowska, E., et al. 2014. Aberrant location of inhibitory synaptic marker proteins in the hippocampus of dystrophin-deficient mice: implications for cognitive impairment in duchenne muscular dystrophy.. PLoS One, e108364.
25220706Siddoway, B., et al. 2014. Potassium channel Kv2.1 is regulated through protein phosphatase-1 in response to increases in synaptic activity.. Neuroscience Letters, 142-7.
24928958McCord, M.C., et al. 2014. Syntaxin-binding domain of Kv2.1 is essential for the expression of apoptotic K+ currents.. The Journal of Physiology, 3511-21.
24723263Dufour, M.A., et al. 2014. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development.. Journal of Neuroscience Research, 981-99.
24647953Shah, N.H., et al. 2014. Cyclin e1 regulates Kv2.1 channel phosphorylation and localization in neuronal ischemia.. Journal of Neuroscience, 4326-31.
24606584Kirizs, T., et al. 2014. Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells.. European Journal of Neuroscience, 1771-83.
24597762Wang, C.Y., et al. 2014. GDF15 regulates Kv2.1-mediated outward K+ current through the Akt/mTOR signalling pathway in rat cerebellar granule cells.. Biochemical Journal, 35-47.
24569993Jensen, C.S., et al. 2014. Specific sorting and post-Golgi trafficking of dendritic potassium channels in living neurons.. The Journal of Biological Chemistry, 10566-81.
24494598Speca, D.J., et al. 2014. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.. Genes, Brain and Behavior, 394-408.
24477962King, A.N., et al. 2014. A unique ion channel clustering domain on the axon initial segment of mammalian neurons.. Journal of Comparative Neurology, 2594-608.
24445605Hund, T.J., et al. 2014. β(IV)-Spectrin regulates TREK-1 membrane targeting in the heart.. Cardiovascular Research, 166-75.
24431441Maguire, E.P., et al. 2014. Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants.. Journal of Neuroscience, 823-38.
24375641Lopez-Izquierdo, A., et al. 2014. The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.. American Journal of Physiology-Heart and Circulatory Physiology, H747-54.
23443966Pirger, Z., et al. 2014. Voltage-gated membrane currents in neurons involved in odor information processing in snail procerebrum.. Brian Structure and Function, 673-82.
24094875Cservenák, M., et al. 2013. Thalamic neuropeptide mediating the effects of nursing on lactation and maternal motivation.. PsychoneuroEndocrinology, 3070-84.
24086760Shepherd, A.J., et al. 2013. Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure.. PLoS One, e76698.
23918396McCord, M.C., et al. 2013. Convergent Ca2+ and Zn2+ signaling regulates apoptotic Kv2.1 K+ currents.. Proceedings of the National Academy of Science of the United States of America, 13988-93.
23878373Guan, D., et al. 2013. Kv2 channels regulate firing rate in pyramidal neurons from rat sensorimotor cortex.. The Journal of Physiology, 4807-25.
23857585Amako, Y., et al. 2013. Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis.. The Journal of Biological Chemistry, 24753-63.
23458708Mavlyutov, T.A., et al. 2013. Lack of sigma-1 receptor exacerbates ALS progression in mice.. Neuroscience, 129-34.
23332758Kourrich, S., et al. 2013. Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine.. Cell, 236-47.
23325261Fox, P.D., et al. 2013. Regulation of Kv2.1 K(+) conductance by cell surface channel density.. Journal of Neuroscience, 1259-70.
23223293Shepherd, A.J., et al. 2012. Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics.. Journal of Neuroscience, 17725-39.
23197740Tsantoulas, C., et al. 2012. Sensory neuron downregulation of the Kv9.1 potassium channel subunit mediates neuropathic pain following nerve injury.. Journal of Neuroscience, 17502-13.
23115240Smith, K.E., et al. 2012. Functional analysis of missense mutations in Kv8.2 causing cone dystrophy with supernormal rod electroretinogram.. The Journal of Biological Chemistry, 43972-83.
22745487Norris, C.A., et al. 2012. Regulation of neuronal proapoptotic potassium currents by the hepatitis C virus nonstructural protein 5A.. Journal of Neuroscience, 8865-70.
22612819Menegola, M., et al. 2012. The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.. Epilepsia, 142-9.
22593583Al-Owais, M.M., et al. 2012. Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition.. The Journal of Biological Chemistry, 24754-64.
22433979Kinoshita, M., et al. 2012. Sigma-1 receptor alters the kinetics of Kv1.3 voltage gated potassium channels but not the sensitivity to receptor ligands.. Brain Research, 1-9.
22411134Dai, X.Q., et al. 2012. The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.. Diabetologia, 1709-20.
22118516Zhou, M.H., et al. 2012. Cholesterol enhances neuron susceptibility to apoptotic stimuli via cAMP/PKA/CREB-dependent up-regulation of Kv2.1.. Journal of Neurochemistry, 502-14.
22106938Song, M.Y., et al. 2012. Dynamic modulation of the kv2.1 channel by SRC-dependent tyrosine phosphorylation.. Journal of Proteome Research, 1018-26.
22056818Peltola, M.A., et al. 2012. AMIGO is an auxiliary subunit of the Kv2.1 potassium channel.. EMBO Reports, 1293-9.
22006306Ikematsu, N., et al. 2011. Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability.. Proceedings of the National Academy of Science of the United States of America, 18132-7.
21911612Joseph, B.K., et al. 2011. Postsynaptic density-95 scaffolding of Shaker-type K⁺ channels in smooth muscle cells regulates the diameter of cerebral arteries.. The Journal of Physiology, 5143-52.
21832084Brittain, J.M., et al. 2011. Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2).. The Journal of Biological Chemistry, 37778-92.
21712386Cerda, O., et al. 2011. Activity-dependent phosphorylation of neuronal Kv2.1 potassium channels by CDK5.. The Journal of Biological Chemistry, 28738-48.
21671801Mihelec, M., et al. 2011. Long-term preservation of cones and improvement in visual function following gene therapy in a mouse model of leber congenital amaurosis caused by guanylate cyclase-1 deficiency.. Human Gene Therapy, 1179-90.
21518833Plant, L.D., et al. 2011. SUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons. Journal of General Physiology, 441-54.
21451062Guan, D., et al. 2011. Postnatal development of A-type and Kv1- and Kv2-mediated potassium channel currents in neocortical pyramidal neurons.. Journal of Neurophysiology, 2976-88.
21412780Zhuang, J.L., et al. 2011. TGF-β1 enhances Kv2.1 potassium channel protein expression and promotes maturation of cerebellar granule neurons.. Journal of Cellular Physiology, 297-307.
21248240Dallas, M.L., et al. 2011. Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1.. The FASEB Journal, 1519-30.
21115483Schwetz, T.A., et al. 2011. Sialic acids attached to O-glycans modulate voltage-gated potassium channel gating.. The Journal of Biological Chemistry, 4123-32.
21110920Song, M.Y., et al. 2011. Contribution of the delayed-rectifier potassium channel Kv2.1 to acute spinal cord injury in rats.. BMB Reports, 756-60.
21092863Nataraj, K., et al. 2010. Visual deprivation suppresses L5 pyramidal neuron excitability by preventing the induction of intrinsic plasticity.. Neuron, 750-62.
20974681Yang, K.C., et al. 2010. Homeostatic regulation of electrical excitability in physiological cardiac hypertrophy.. The Journal of Physiology, 5015-32.
20202934Kihira, Y., et al. 2010. Formation of heteromeric Kv2 channels in mammalian brain neurons.. The Journal of Biological Chemistry, 15048-55.
20167253Mavlyutov, T.A., et al. 2010. The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study.. Neuroscience, 247-55.
20079839Ito, T., et al. 2010. Regulation of Kv2.1 phosphorylation in an animal model of anoxia.. Neurobiology of Disease, 85-91.
19744491Tozakidou, M., et al. 2010. Molecular and functional remodeling of I(to) by angiotensin II in the mouse left ventricle.. Journal of Molecular and Cellular Cardiology, 140-51.
20092568Aras, M.A., et al. 2009. Zn2+ regulates Kv2.1 voltage-dependent gating and localization following ischemia.. European Journal of Neuroscience, 2250-7.
19717445Mankouri, J., et al. 2009. Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence.. Proceedings of the National Academy of Science of the United States of America, 15903-8.
19344330Eyre, M.D., et al. 2009. Molecular diversity of deep short-axon cells of the rat main olfactory bulb.. European Journal of Neuroscience, 1397-407.
19185209Mulholland, P.J., et al. 2009. Ethanol disrupts NMDA receptor and astroglial EAAT2 modulation of Kv2.1 potassium channels in hippocampus.. Alcohol, 45-50.
18753382Mulholland, P.J., et al. 2008. Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels.. Journal of Neuroscience, 8801-9.
18716211Misonou, H., et al. 2008. Dynamic regulation of the Kv2.1 voltage-gated potassium channel during brain ischemia through neuroglial interaction.. Journal of Neuroscience, 8529-38.
17610815Micheva, K.D., et al. 2007. Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits.. Neuron, 25-36.
17379638Guan, D., et al. 2007. Kv2 subunits underlie slowly inactivating potassium current in rat neocortical pyramidal neurons.. The Journal of Physiology, 941-60.
16943244Pott, C., et al. 2007. Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice.. American Journal of Physiology-Cell Physiology, C968-73.
17192433Misonou, H., et al. 2006. Bidirectional activity-dependent regulation of neuronal ion channel phosphorylation.. Journal of Neuroscience, 13505-14.

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