Anti-Nav1.7 Na+ Channel Antibody (N68/6)


Primary Antibody
Human, Mouse, Rat
N68/6
IHC, IP, WB
Mouse
Purified
SCN9A NENA
230 kDa

Go to Full Product Details


Anti-Nav1.7 Na+ Channel Antibody
SKU: 75-103

Volume: 100 µL
Price:
Sale price$345


Bulk Order Anti-Nav1.7 Na+ Channel Antibody

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
349309441:250Alsaloum, M., et al. 2021. Contributions of NaV1.8 and NaV1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons. Scientific Reports, 24283.
Immunocytochemistry: Mouse
PMID Dilution Publication
259954841:400Lu, V.B., et al. 2015. A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animal.. Journal of Neuroscience, 8021-34.
189886731:100Ernst, S.J., et al. 2009. Sodium channel beta1 regulatory subunit deficiency reduces pancreatic islet glucose-stimulated insulin and glucagon secretion.. Endocrinology, 1132-9.
Immunocytochemistry: Rat
PMID Dilution Publication
315014501:500Vysokov, N., et al. 2019. The role of Na V channels in synaptic transmission after axotomy in a microfluidic culture platform. Scientific Reports, 12915.
27940916not listedDustrude, E.T., et al. 2016. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. PNAS, E8443-52.
214867031:500Chattopadhyay, M., et al. 2011. Vector-mediated release of GABA attenuates pain-related behaviors and reduces Na(V)1.7 in DRG neurons.. European Journal of Pain, 913-20.
206354061:250Cox, J.J., et al. 2010. Congenital insensitivity to pain: novel SCN9A missense and in-frame deletion mutations.. Human Mutation, 1670-86.
Immunohistochemistry: Human
PMID Dilution Publication
335506282ug/mlShiers, S.I., et al. 2021. Convergence of peptidergic and non-peptidergic protein markers in the human dorsal root ganglion and spinal dorsal horn. The Journal of Comparative Neurology, 2771-88.
Immunohistochemistry: Mouse
PMID Dilution Publication
30125271not listedNunes, D., et al. 2018. Axonal sodium channel NaV1. 2 drives granule cell dendritic GABA release and rapid odor discrimination. . PLoS Biology, e2003816.
Immunohistochemistry: Rat
PMID Dilution Publication
363589211:200Reid, A., et al. 2022. Long-Term Blockade of Nociceptive Nav1.7 Channels Is Analgesic in Rat Models of Knee Arthritis. Biomolecules, 1571.
315509955 µg/mLGrubinska, B., et al. 2019. Rat Na V 1.7 loss-of-function genetic model: Deficient nociceptive and neuropathic pain behavior with retained olfactory function and intra-epidermal nerve fibers. Molecular Pain, 1744806919881840.
2364240825 µg/mLLiang, L., et al. 2013. Protein kinase B/Akt is required for complete Freund''s adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neurons.. The Journal of Pain, 638-47.
230222181:100Cachemaille, M., et al. 2012. Neuronal expression of the ubiquitin ligase Nedd4-2 in rat dorsal root ganglia: modulation in the spared nerve injury model of neuropathic pain.. Neuroscience, 370-80.
Immunoprecipitation: Rat
PMID Dilution Publication
2995658610 ugDash, B., et al. 2018. Nonmuscle myosin II isoforms interact with sodium channel alpha subunits. . Molecular Pain, 1744806918788630.
Western Blot: Human
PMID Dilution Publication
24009557not listedLaedermann, C.J., et al. 2013. β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells.. Frontiers in Neuroscience, 137.
23986482not listedCampbell, T.M., et al. 2013. Functional expression of the voltage-gated Na⁺-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cells.. Journal of Cell Science, 4939-49.
Western Blot: Mouse
PMID Dilution Publication
351318651:500Deftu, A.F., et al. 2022. The anti-diabetic drug metformin regulates voltage-gated sodium channel NaV1.7 via the ubiquitin-ligase NEDD4-2. eNeuro, ENEURO.0409-21.2022.
30125271not listedNunes, D., et al. 2018. Axonal sodium channel NaV1. 2 drives granule cell dendritic GABA release and rapid odor discrimination. . PLoS Biology, e2003816.
276044201:500Yanpallewar, S., et al. 2016. Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli. Scientific Reports, 32957.
256206051:500Vandael, D.H., et al. 2015. Reduced availability of voltage-gated sodium channels by depolarization or blockade by tetrodotoxin boosts burst firing and catecholamine release in mouse chromaffin cells.. The Journal of Physiology, 905-27.
236079661:100Melemedjian, O.K., et al. 2013. mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK.. Pain, 1080-91.
23095258not listedLiu, J., et al. 2012. Voltage-gated sodium channel expression and action potential generation in differentiated NG108-15 cells.. BMC Neuroscience, 129.
Western Blot: Rat
PMID Dilution Publication
3155099510 µgGrubinska, B., et al. 2019. Rat Na V 1.7 loss-of-function genetic model: Deficient nociceptive and neuropathic pain behavior with retained olfactory function and intra-epidermal nerve fibers. Molecular Pain, 1744806919881840.
27940916not listedDustrude, E.T., et al. 2016. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. PNAS, E8443-52.
236424081:1000Liang, L., et al. 2013. Protein kinase B/Akt is required for complete Freund''s adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neurons.. The Journal of Pain, 638-47.
23095258not listedLiu, J., et al. 2012. Voltage-gated sodium channel expression and action potential generation in differentiated NG108-15 cells.. BMC Neuroscience, 129.
2240825510 µgHo, C., et al. 2012. Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons.. The Journal of Biological Chemistry, 15044-53.
22273495not listedYan, J., et al. 2012. Sensitization of dural afferents underlies migraine-related behavior following meningeal application of interleukin-6 (IL-6).. Molecular Pain, 6.
Additional Publications: Unspecified
PMID Publication
30894674Bugan, I., et al. 2019. Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate. Prostate Cancer and Prostatic Diseases, 569-79.
30565051Yu, J., et al. 2019. Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission. Molecular Neurobiology, 5241-55.
29655575Moutal, A., et al. 2018. CRMP2-Neurofibromin Interface Drives NF1-related Pain. Neuroscience, 79-90.
23836888Dustrude, E.T., et al. 2013. CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.. The Journal of Biological Chemistry, 24316-31.
22071319Tappe-Theodor, A., et al. 2012. Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization.. Pain, 184-96.

Related Products

Recently Viewed