Immunostaining of primary rat cortical neuroepithelial cells with anti-Olig2 (cat # 1538-OLIG2, red, 1:1000). The cells were treated with basic FGF for 30 hours prior to staining (this induces Olig2 expression in these primary cells).

Immunostaining of primary rat cortical neuroepithelial cells with anti-Olig2 (cat # 1538-OLIG2, red, 1:1000). The cells were treated with basic FGF for 30 hours prior to staining (this induces Olig2 expression in these primary cells).

Anti-Olig2

Anti-Olig2

Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~32 kDa Olig2 protein.

Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~32 kDa Olig2 protein.

from PhosphoSolutions

Anti-Olig2 (1538-Olig2)

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Product Details


Details

Volume: 100 µL (Standard), 25 µL (Trial Size)

Concentration: Lot Specific

Clonality: Polyclonal

Form: Protein A purified

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IP

Immunogen: Recombinant mouse Olig2

Protein Name / Synonyms: Olig

Target Description: Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007)

Gene ID: OLIG2

Antibody Registry ID (RRID): AB_2492193

Physical State: Liquid

Conjugate: Unconjugated

Buffer: 100 µl in 100 mM Glycine, 200 mM Tris, pH 8.0

Validation and Application Notes

Molecular Weight: 27

Storage

-20 C

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.


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