Immunostaining of mouse retinal ganglion cells showing specific immunolabeling of RBPMS (1:1000) in red. Photo courtesy of Allen Rodriguez, University of California, Los Angeles.

Immunostaining of mouse retinal ganglion cells showing specific immunolabeling of RBPMS (1:1000) in red. Photo courtesy of Allen Rodriguez, University of California, Los Angeles.

Western blot of rat heart lysate showing specific labeling of the ~24 kDa RBPMS protein.

Western blot of rat heart lysate showing specific labeling of the ~24 kDa RBPMS protein.

Anti-RBPMS (1830-RBPMS)

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Product Details


Details

RBPMS (RNA binding protein with multiple splicing), also known as HERMES, contains one RRM (RNA recognition motif) domain and belongs to the RRM family of RNA-binding proteins. RBPMS exists as multiple alternatively spliced isoforms and is thought to bind RNA, possibly playing a role in RNA-related events, such as transcription and translation. RNA-binding proteins that are specific to retinal ganglion cells (RGCs) have been previously identified as excellent markers for RGCs (Kwong et al., 2010). Recent findings show that antibodies against RBPMS are robust reagents that exclusively identify RGCs in multiple mammalian species (Rodriguez et al. 2014)

Volume: 100 µL

Concentration: Lot Specific

Clonality: Polyclonal

Form: Antigen Affinity Purified

Host Species: Rabbit

Species Reactivity: Guinea Pig, Mouse, non-Human primate, Rabbit, Rat

Applications: WB, IHC

Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Protein Name / Synonyms: rpbms

Gene ID: RBPMS

Antibody Registry ID (RRID): AB_2492225

Physical State: Liquid

Conjugate: Unconjugated

Buffer: 100 ul in PBS + 0.03% NaN3

Validation and Application Notes

Molecular Weight: 24

Storage

-20 C

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.


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