Immunostaining of mouse retinal ganglion cells showing specific immunolabeling of RBPMS (1:1000) in red. Photo courtesy of Allen Rodriguez, University of California, Los Angeles.
Details
RBPMS (RNA binding protein with multiple splicing), also known as HERMES, contains one RRM (RNA recognition motif) domain and belongs to the RRM family of RNA-binding proteins. RBPMS exists as multiple alternatively spliced isoforms and is thought to bind RNA, possibly playing a role in RNA-related events, such as transcription and translation. RNA-binding proteins that are specific to retinal ganglion cells (RGCs) have been previously identified as excellent markers for RGCs (Kwong et al., 2010). Recent findings show that antibodies against RBPMS are robust reagents that exclusively identify RGCs in multiple mammalian species (Rodriguez et al. 2014)
Volume: 100 µL
Concentration: Lot Specific
Clonality: Polyclonal
Form: Antigen Affinity Purified
Host Species: Rabbit
Species Reactivity: Guinea Pig, Mouse, non-Human primate, Rabbit, Rat
Applications: WB, IHC
Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Protein Name / Synonyms: rpbms
Gene ID: RBPMS
Antibody Registry ID (RRID): AB_2492225
Physical State: Liquid
Conjugate: Unconjugated
Buffer: 100 ul in PBS + 0.03% NaN3
Validation and Application Notes
Molecular Weight: 24
Storage
-20 C
NOTE
Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.