Immunostaining of 40DIV cultured rat cortical neurons showing punctate labeling of synapsin (cat #1926-SYNP, 1:1000, red). The blue is staining nuclear DNA. Cells and photo courtesy of QBMCellScience.

Immunostaining of 40DIV cultured rat cortical neurons showing punctate labeling of synapsin (cat #1926-SYNP, 1:1000, red). The blue is staining nuclear DNA. Cells and photo courtesy of QBMCellScience.

Immunostaining of cultured mouse caudate neurons showing punctate distribution of synapsin (catalog # 1926-SYNP, 1:1000, green) and MAP (red). Cells and photo courtesy of QBMCellScience.

Immunostaining of cultured mouse caudate neurons showing punctate distribution of synapsin (catalog # 1926-SYNP, 1:1000, green) and MAP (red). Cells and photo courtesy of QBMCellScience.

Western blot of 10 ug of rat hippocampal lysate showing specific immunolabeling of the ~78 kDa synapsin I doublet protein.

Western blot of 10 ug of rat hippocampal lysate showing specific immunolabeling of the ~78 kDa synapsin I doublet protein.

Anti-Synapsin I (100 ul) (1926-SYNP)

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Product Details


Details

Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002; Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989; Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogenesis is regulated by phosphorylation (Jovanovic et al., 2001; Kao et al., 2002).

Volume: 100 µL

Concentration: Lot Specific

Clonality: Polyclonal

Form: Antigen Affinity Purified from Pooled Serum

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Applications: WB, IF, IP, IHC

Immunogen: Native protein purified from bovine brain

Gene ID: SYN1

Antibody Registry ID (RRID): AB_2492242

Physical State: Liquid

Conjugate: Unconjugated

Buffer: 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Validation and Application Notes

Molecular Weight: 78

Storage

-20 C

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.


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