Anti-Tyrosine Hydroxylase (Ser40) Antibody

Our Anti-Tyrosine Hydroxylase (Ser40) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects many mammalian, and many non-mammalian Tyrosine Hydroxylase (Ser40) and is antigen affinity purified from pooled serum. It is great for use in WB, IHC, ICC.



SKU: p1580-40

Volume: 100 µL
Price:
Sale price$430

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
28637871 1:50 Jorge-Finnigan, A., et al. 2017. Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules. Journal of Biological Chemistry, 292(34), pp.14092-14107.
Immunocytochemistry: Rat
PMID Dilution Publication
32778969 1:3000 Nakashima, A., et al. 2020. NT5DC2 affects the phosphorylation of tyrosine hydroxylase regulating its catalytic activity. Journal of Neural Transmission, pp.1-10.
28637871 1:50 Jorge-Finnigan, A., et al. 2017. Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules. Journal of Biological Chemistry, 292(34), pp.14092-14107.
10936746 1:300 Witkovsky, P, et al. 2000. Influence of light and neural circuitry on tyrosine hydroxylase phosphorylation in the rat retina. Journal of chemical neuroanatomy, 19(2), pp.105-116.
Western Blot: Human
PMID Dilution Publication
28637871 1:1000 Jorge-Finnigan, A., et al. 2017. Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules. Journal of Biological Chemistry, 292(34), pp.14092-14107.
11677263 not listed Salvatore, M.F, et al. 2001. Depolarization‐stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ. Journal of neurochemistry, 79(2), pp.349-360.
Western Blot: Mouse
PMID Dilution Publication
371332181:1000Le, VQ, et al. 2023. Extracellular H+ Ions are a Novel Signal for Tyrosine Hydroxylase Activation in Catecholaminergic Cells. ACS Chemical Neuroscience, 1774-1784.
30803445 1:1000 Areal, L.B., et al. 2019. Neuronal scaffolding protein spinophilin is integral for cocaine-induced behavioral sensitization and ERK1/2 activation. Molecular brain, 12(1), p.15.
29782882 1:1000 Salvatore, M.F., et al. 2018. Prolonged increase in ser31 tyrosine hydroxylase phosphorylation in substantia nigra following cessation of chronic methamphetamine. Neurotoxicology, 67, pp.121-128.
29299922 not listed Bezem, M.T., et al. 2018. Stabilization of human tyrosine hydroxylase in maltodextrin nanoparticles for delivery to neuronal cells and tissue. Bioconjugate Chemistry Feb 21;29(2):493-502.
27124386 not listed Salvatore, M.F., et al. 2016. Regulation of tyrosine hydroxylase expression and phosphorylation in dopamine transporter-deficient mice. ACS chemical neuroscience, 7(7), pp.941-951.
19017804 not listed Meyer, D.A., et al. 2008. Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology. PNAS, 105: 18561 - 18566.
Western Blot: Rat
PMID Dilution Publication
378653391:1000Szigetvari, PD, et al. 2023. The effects of phenylalanine and tyrosine levels on dopamine production in rat PC12 cells. Implications for treatment of phenylketonuria, tyrosinemia type 1 and comorbid neurodevelopmental disorders. Neurochemistry international, 105629.
376346961:1000Kasanga, EA, et al. 2023. Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs. Experimental Neurology, 114509.
32778969 not listed Nakashima, A., et al. 2020. NT5DC2 affects the phosphorylation of tyrosine hydroxylase regulating its catalytic activity. Journal of Neural Transmission, pp.1-10.
28637871 1:1000 Jorge-Finnigan, A., et al. 2017. Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules. Journal of Biological Chemistry, 292(34), pp.14092-14107.
28637176 1:1000 Salvatore, M.F., et al. 2017. Dissociation of striatal dopamine and tyrosine hydroxylase expression from aging-related motor decline: evidence from calorie restriction intervention. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, Dec 12;73(1):11-20.
26777664 1:1000 Baroso-Chinea, P., et al. 2016. Long-term controlled GDNF over-expression reduces dopamine transporter activity without affecting tyrosine hydroxylase expression in the mesostriatal system rat. Neurobiology of Disease, 88:44-54.
24743698 not listed Izumi, Y, et al. 2014. Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death. Toxicological Sciences, 139(2), pp.466-478.
24410633 1:1000 Salvatore, M.F., et al. 2014. ser31 tyrosine hydroxylase phosphorylation parallels differences in dopamine recovery in nigrostriatal pathway following 6‐OHDA lesion. Journal of neurochemistry, 129(3), 548-558.
22723669 1:100,000 McCutcheon, J.E., et al. 2012. Dopamine neurons in the ventral tegmental area fire faster in adolescent rats than in adults. J Neurophysiology 108(6): 1620-1630.
22458761 1:2000 Calipari, E.S., et al. 2014. Methylphenidate and cocaine self‐administration produce distinct dopamine terminal alterations. Addiction biology, 19(2), pp.145-155.
12124439 1:1500 Jedynak, J.P., et al. 2002. Acute administration of cocaine regulates the phosphorylation of serine‐19,‐31 and‐40 in tyrosine hydroxylase. Journal of neurochemistry, 82(2), pp.382-388.
11677263 not listed Salvatore, M.F, et al. 2001. Depolarization‐stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ. Journal of neurochemistry, 79(2), pp.349-360.

Bulk Order Anti-Tyrosine Hydroxylase (Ser40) Antibody

Product Specific Protocols

  • Tyrosine Hydroxylase Ser40 ICC Protocol: Download

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