Immunoblot on brain membranes from wild-type (WT) and Kv1.2 knockout (Kv1.2-/-) mice and from adult rat brain (RBM).

Immunoblot on brain membranes from wild-type (WT) and Kv1.2 knockout (Kv1.2-/-) mice and from adult rat brain (RBM).

Adult rat hippocampus immunohistochemistry.

Adult rat hippocampus immunohistochemistry.

Adult rat brain membrane immunoblot.

Adult rat brain membrane immunoblot.

Immunoblot on membranes from whole rat (RBM) and mouse (MBM) brain and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].

Immunoblot on membranes from whole rat (RBM) and mouse (MBM) brain and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].

from NeuroMab

Kv1.2 K+ channel (7x-008)

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Product Details | ↓ Citations



Volume: Purified: 100 µL; Purified Trial: 20 µL; TC Supernatant: 5 mL

Concentration: Purified: 1 mg/mL; TC Supernatant: Lot Specific

Clonality: Monoclonal

Form: Purified and TC Supernatant Available (select your preferred form, size and quantity before clicking "Add to Cart")

Host Species: Mouse

Immunogen: Fusion protein amino acids 428-499(cytoplasmic C-terminus) of rat Kv1.2 (accession number P63142), Epitope mapped to within amino acids 463-480
Human: 100% identity
Mouse: 100% identity

Target Description: Kv1.2 K+ channel (Potassium voltage-gated channel subfamily A member 2), which is encoded by KCNA2 gene, is part of the Potassium voltage-gated channel family. Kv1.2 K+ channel switches between its open and closed conformation in response to the voltage difference across the membrane, which selectively allows the traffic of K+. Kv1.2 K+ channel determines potassium ion permeability of excitable membranes according to their electrochemical gradient. Therefore, this protein has for function to regulate neurotransmitter release, neuronal excitability, smooth muscle contraction, heart muscle contraction or insulin secretion. Kv1.2 is recognized as a tansmembrane/ multi-pass membrane protein. Anti-Kv1.2 K+ channel K14/16 is often used in IHC on human normal cerebral cortex.

Gene ID: KCNA2

Antibody Registry ID (RRID): AB_2296313

Physical State: Liquid

Validation and Application Notes

Molecular Weight: 80 kDa

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.


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Citations


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