Immunostaining of mouse retinal ganglion cells showing specific immunolabeling of RBPMS (1:1000) in red. Photo courtesy of Allen Rodriguez, University of California, Los Angeles.
RBPMS (RNA binding protein with multiple splicing), also known as HERMES, contains one RRM (RNA recognition motif) domain and belongs to the RRM family of RNA-binding proteins. RBPMS exists as multiple alternatively spliced isoforms and is thought to bind RNA, possibly playing a role in RNA-related events, such as transcription and translation. RNA-binding proteins that are specific to retinal ganglion cells (RGCs) have been previously identified as excellent markers for RGCs (Kwong et al., 2010). Recent findings show that antibodies against RBPMS are robust reagents that exclusively identify RGCs in multiple mammalian species (Rodriguez et al. 2014)
Antigen Affinity Purified
Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH(Rat)
Guinea Pig, Mouse, non-Human primate, Rabbit, Rat
100 ul in PBS + 0.03% NaN3
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After date of receipt, stable for at least 1 year at -20°C.